학술논문

Distinct Dimensions of Kidney Health and Risk of Cardiovascular Disease, Heart Failure, and Mortality
Document Type
article
Source
Hypertension. 74(4)
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Cardiovascular
Clinical Research
Prevention
Heart Disease
Kidney Disease
Renal and urogenital
Good Health and Well Being
Aged
Aged
80 and over
Biomarkers
Blood Pressure
Cardiovascular Diseases
Creatinine
Female
Glomerular Filtration Rate
Humans
Kidney
Male
Middle Aged
Renal Insufficiency
Chronic
Risk
Survival Rate
albuminuria
biomarker
cardiovascular diseases
epidemiology
kidney
Cardiorespiratory Medicine and Haematology
Public Health and Health Services
Cardiovascular System & Hematology
Cardiovascular medicine and haematology
Clinical sciences
Language
Abstract
Chronic kidney disease is a strong risk factor for cardiovascular disease (CVD), but clinical kidney measures (estimated glomerular filtration rate and albuminuria) do not fully reflect the multiple aspects of kidney tubules influencing cardiovascular health. Applied methods are needed to integrate numerous tubule biomarkers into useful prognostic scores. In SPRINT (Systolic Blood Pressure Intervention Trial) participants with chronic kidney disease at baseline (estimated glomerular filtration ratecr&cys