학술논문
Particulate Matter, Endotoxin, and Worker Respiratory Health on Large Californian Dairies
Document Type
article
Author
Source
Journal of Occupational and Environmental Medicine. 57(1)
Subject
Language
Abstract
ObjectiveTo assess respiratory exposures and lung function in a cross-sectional study of California dairy workers.MethodsExposure of 205 dairy and 45 control (vegetable processing) workers to particulate matter and endotoxin was monitored. Pre- and postshift spirometry and interviews were conducted.ResultsGeometric mean inhalable and PM2.5 concentrations were 812 and 35.3 μg/m3 versus 481.9 and 19.6 μg/m3, respectively, for dairy and control workers. Endotoxin concentrations were 329 EU/m3 or 1122 pmol/m3 and 13.5 EU/m3 or 110 pmol/m3, respectively, for dairy and control workers. In a mixed-effects model, forced vital capacity decreased across a work shift by 24.5 mL (95% confidence interval, -44.7 to -4.3; P = 0.018) with log10 (total endotoxin) and by 22.0 mL (95% confidence interval, -43.2 to -0.08; P = 0.042) per hour worked.ConclusionsModern California dairy endotoxin exposures and shift length were associated with a mild acute decrease in forced vital capacity.