학술논문

Depression in Chinese patients with type 2 diabetes: associations with hyperglycemia, hypoglycemia, and poor treatment adherence.
Document Type
article
Source
Journal of diabetes. 7(6)
Subject
China Depression in Chinese Patients with Type 2 Diabetes (DD2) Study Group
Humans
Diabetes Mellitus
Type 2
Hyperglycemia
Hypoglycemia
Blood Glucose
Hypoglycemic Agents
Treatment Outcome
Self Care
Health Care Surveys
Logistic Models
Odds Ratio
Risk Factors
Chi-Square Distribution
Cross-Sectional Studies
Depression
Aged
Middle Aged
Asian Continental Ancestry Group
China
Female
Male
Medication Adherence
Biomarkers
Surveys and Questionnaires
depression
hyperglycemia
hypoglycemia
treatment adherence
type 2 diabetes
关键词:抑郁、高血糖、低血糖、治疗依从性、2型糖尿病
Diabetes Mellitus
Type 2
Clinical Sciences
Public Health and Health Services
Language
Abstract
BackgroundWe hypothesize that depression in type 2 diabetes might be associated with poor glycemic control, in part due to suboptimal self-care. We tested this hypothesis by examining the associations of depression with clinical and laboratory findings in a multicenter survey of Chinese type 2 diabetic patients.Method2538 patients aged 18-75 years attending hospital-based clinics in four cities in China underwent detailed clinical-psychological-behavioral assessment during a 12-month period between 2011 and 2012. Depression was diagnosed if Patient Health Questionnaire-9 (PHQ-9) score ≥10. Diabetes self-care and medication adherence were assessed using the Summary of Diabetes Self-care Activities and the 4-item Morisky medication adherence scale respectively.ResultsIn this cross-sectional study (mean age: 56.4 ± 10.5[SD] years, 53% men), 6.1% (n = 155) had depression. After controlling for study sites, patients with depression had higher HbA(1c) (7.9 ± 2.0 vs. 7.7 ± 2.0%, P = 0.008) and were less likely to achieve HbA(1c) goal of