학술논문

EcoCyc: fusing model organism databases with systems biology
Document Type
article
Source
Nucleic Acids Research. 41(D1)
Subject
Genetics
Human Genome
Infection
Binding Sites
Databases
Genetic
Escherichia coli K12
Escherichia coli Proteins
Gene Expression Regulation
Bacterial
Internet
Membrane Transport Proteins
Models
Genetic
Molecular Sequence Annotation
Phenotype
Position-Specific Scoring Matrices
Promoter Regions
Genetic
Systems Biology
Transcription Factors
Transcription
Genetic
Environmental Sciences
Biological Sciences
Information and Computing Sciences
Developmental Biology
Language
Abstract
EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.