학술논문

Sexual function remains persistently low in women after treatment for colorectal cancer and anal squamous cell carcinoma.
Document Type
article
Source
The Journal of Sexual Medicine. 20(4)
Subject
anal squamous cell carcinoma
cancer survivorship
colorectal cancer
female hypoactive desire disorder
female sexual dysfunction
pelvic radiation
Female
Humans
Middle Aged
Sexual Dysfunctions
Psychological
Prospective Studies
Sexual Behavior
Sexual Dysfunction
Physiological
Carcinoma
Squamous Cell
Rectal Neoplasms
Surveys and Questionnaires
Language
Abstract
BACKGROUND: Women diagnosed with colorectal cancer (CRC) or anal squamous cell carcinoma (ASCC) are at high risk of sexual dysfunction after treatment, yet little is known about recovery and risk factors for chronic dysfunction. AIM: We aimed to describe sexual function and sexual activity among women who underwent definitive treatment for CRC or ASCC, examine relationships between time since treatment completion and sexual function, and explore factors associated with desire and changes in sexual desire over time. METHODS: As part of a prospective cohort study of patients with gastrointestinal cancer at the University of California San Francisco, female-identifying participants who finished definitive treatment for CRC or ASCC completed the Female Sexual Function Index (FSFI) at 6- to 12-month intervals. We used multivariable linear mixed models to explore factors associated with the FSFI desire subscale. OUTCOMES: Outcomes were rates of sexual activity, proportion at risk for sexual dysfunction (FSFI score