학술논문
Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
Document Type
article
Author
Elena, Joanne W; Steplowski, Emily; Yu, Kai; Hartge, Patricia; Tobias, Geoffrey S; Brotzman, Michelle J; Chanock, Stephen J; Stolzenberg-Solomon, Rachael Z; Arslan, Alan A; Bueno-de-Mesquita, H Bas; Helzlsouer, Kathy; Jacobs, Eric J; LaCroix, Andrea; Petersen, Gloria; Zheng, Wei; Albanes, Demetrius; Allen, Naomi E; Amundadottir, Laufey; Bao, Ying; Boeing, Heiner; Boutron-Ruault, Marie-Christine; Buring, Julie E; Gaziano, J Michael; Giovannucci, Edward L; Duell, Eric J; Hallmans, Göran; Howard, Barbara V; Hunter, David J; Hutchinson, Amy; Jacobs, Kevin B; Kooperberg, Charles; Kraft, Peter; Mendelsohn, Julie B; Michaud, Dominique S; Palli, Domenico; Phillips, Lawrence S; Overvad, Kim; Patel, Alpa V; Sansbury, Leah; Shu, Xiao-Ou; Simon, Michael S; Slimani, Nadia; Trichopoulos, Dimitrios; Visvanathan, Kala; Virtamo, Jarmo; Wolpin, Brian M; Zeleniuch-Jacquotte, Anne; Fuchs, Charles S; Hoover, Robert N; Gross, Myron
Source
Cancer Causes & Control. 24(1)
Subject
Language
Abstract
PurposeDiabetes is a suspected risk factor for pancreatic cancer, but questions remain about whether it is a risk factor or a result of the disease. This study prospectively examined the association between diabetes and the risk of pancreatic adenocarcinoma in pooled data from the NCI pancreatic cancer cohort consortium (PanScan).MethodsThe pooled data included 1,621 pancreatic adenocarcinoma cases and 1,719 matched controls from twelve cohorts using a nested case-control study design. Subjects who were diagnosed with diabetes near the time (