학술논문
Cross-sectional characteristics of pediatric-onset discoid lupus erythematosus: Results of a multicenter, retrospective cohort study
Document Type
article
Author
Ezeh, N; Ardalan, K; Buhr, KA; Nguyen, C; Ahmed, O Al; Ardoin, SP; Barton, V; Bell, S; Brandling-Bennett, H; Castelo-Soccio, L; Chiu, YE; Chong, BF; Co, DO; Lara-Corrales, I; Cintosun, A; Curran, ML; Diaz, LZ; Elman, SA; Faith, E Fernandez; Garcia-Romero, MT; Grossman-Kranseler, J; Hogeling, M; Hudson, AD; Hunt, RD; Ibler, EM; Marques, MC; Monir, RL; Oza, V; Paller, AS; Putterman, E; Rodriguez-Salgado, P; Schoch, JJ; Truong, A; Wang, J; Lee, L Wine; Vleugels, RA; Klein-Gitelman, MS; von Scheven, E; Werth, VP; Arkin, Lisa M
Source
Journal of the American Academy of Dermatology. 87(3)
Subject
Language
Abstract
BackgroundThe incidence of systemic lupus in children with discoid lupus is unknown.ObjectiveThis study assessed the baseline characteristics of patients with pediatric discoid lupus erythematosus (pDLE).MethodsMedical records at 17 sites were reviewed for pediatric dermatology and rheumatology patients with discoid lupus erythematosus. The inclusion criteria were clinical and/or histopathologic diagnosis of discoid lupus erythematosus with an age at onset of 1500 charts reviewed, 438 patients met the inclusion criteria. The cohort was predominantly female (72%) and racially/ethnically diverse. A diagnosis of SLE at the baseline visit (pDLE + SLE) was rendered in 162 (37%) patients using the American College of Rheumatology and in 181 (41%) patients using the Systemic Lupus International Collaborating Clinics criteria. Patients with pDLE + SLE were older at the time of rash onset (median, 12.9 vs 8.9 years; P