학술논문

Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network
Document Type
article
Source
Pediatrics. 141(5)
Subject
Neurosciences
Intellectual and Developmental Disabilities (IDD)
Brain Disorders
Perinatal Period - Conditions Originating in Perinatal Period
Preterm
Low Birth Weight and Health of the Newborn
Cerebral Palsy
Pediatric
Clinical Research
Infant Mortality
Reproductive health and childbirth
Cognitive Dysfunction
Developmental Disabilities
Female
Gestational Age
Humans
Infant
Extremely Premature
Infant
Newborn
Male
Motor Disorders
Neurologic Examination
Retrospective Studies
Risk Factors
Sensation Disorders
Severity of Illness Index
Socioeconomic Factors
Follow-Up Study of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Medical and Health Sciences
Psychology and Cognitive Sciences
Pediatrics
Language
Abstract
Evaluate the spectrum of neurodevelopmental outcome in a contemporary cohort of extremely preterm infants. We hypothesize that the rate of severe neurodevelopmental impairment (NDI) decreases over time. Retrospective analysis of neurodevelopmental outcome of preterm infants ≤27 weeks' gestational age (GA) from a Neonatal Research Network center that completed neurodevelopmental follow-up assessments between April 1, 2011, and January 1, 2015. The Bayley Scales of Infant Development-III (BSID III) and a standardized neurosensory examination were performed between 18 and 26 months' adjusted age. Outcome measures were neurologic examination diagnoses, BSID III cognitive and motor scores, sensory impairment, and the composite outcome of NDI, based on the BSID III cognitive score (analyzed by using a cutoff of