학술논문

Replacing cyclophosphamide/cytarabine/mercaptopurine with cyclophosphamide/etoposide during consolidation/delayed intensification does not improve outcome for pediatric B-cell acute lymphoblastic leukemia: a report from the COG
Document Type
article
Source
Haematologica. 104(5)
Subject
Biomedical and Clinical Sciences
Cardiovascular Medicine and Haematology
Oncology and Carcinogenesis
Orphan Drug
Clinical Trials and Supportive Activities
Hematology
Rare Diseases
Cancer
Clinical Research
Patient Safety
Pediatric Cancer
Pediatric
Childhood Leukemia
6.1 Pharmaceuticals
Evaluation of treatments and therapeutic interventions
Good Health and Well Being
Adolescent
Adult
Antineoplastic Combined Chemotherapy Protocols
Case-Control Studies
Child
Child
Preschool
Cyclophosphamide
Cytarabine
Etoposide
Female
Follow-Up Studies
Humans
Infant
Male
Mercaptopurine
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Prognosis
Prospective Studies
Survival Rate
Young Adult
Cardiorespiratory Medicine and Haematology
Immunology
Cardiovascular medicine and haematology
Language
Abstract
With modern chemotherapy, approximately 90% of patients with pediatric acute lymphoblastic leukemia are now cured. However, subsets of patients can be identified who remain at very high risk of relapse with expected 4-year disease-free survival rates