학술논문

EVpedia: a community web portal for extracellular vesicles research
Document Type
article
Author
Kim, Dae-KyumLee, JaewookKim, Sae RomChoi, Dong-SicYoon, Yae JinKim, Ji HyunGo, GyeongyunNhung, DinhHong, KahyeJang, Su ChulKim, Si-HyunPark, Kyong-SuKim, Oh YounPark, Hyun TaekSeo, Ji HyeAikawa, ElenaBaj-Krzyworzeka, Monikavan Balkom, Bas WMBelting, MattiasBlanc, LionelBond, VincentBongiovanni, AntonellaBorràs, Francesc EBuée, LucBuzás, Edit ICheng, LesleyClayton, AledCocucci, EmanueleDela Cruz, Charles SDesiderio, Dominic MDi Vizio, DoloresEkström, KarinFalcon-Perez, Juan MGardiner, ChrisGiebel, BerndGreening, David WGross, Julia ChristinaGupta, DwijendraHendrix, AnHill, Andrew FHill, Michelle MNolte-'t Hoen, EstherHwang, Do WonInal, JameelJagannadham, Medicharla VJayachandran, MuthuvelJee, Young-KooJørgensen, MaleneKim, Kwang PyoKim, Yoon-KeunKislinger, ThomasLässer, CeciliaLee, Dong SooLee, Hakmovan Leeuwen, JohannesLener, ThomasLiu, Ming-LinLötvall, JanMarcilla, AntonioMathivanan, SureshMöller, AndreasMorhayim, JessMullier, FrançoisNazarenko, IrinaNieuwland, RienkNunes, Diana NPang, KenPark, JaesungPatel, TusharPocsfalvi, GabriellaDel Portillo, HernandoPutz, UlrichRamirez, Marcel IRodrigues, Marcio LRoh, Tae-YoungRoyo, FelixSahoo, SusmitaSchiffelers, RaymondSharma, ShivaniSiljander, PiaSimpson, Richard JSoekmadji, CarolinaStahl, PhilipStensballe, AllanStępień, EwaTahara, HidetoshiTrummer, ArneValadi, HadiVella, Laura JWai, Sun NyuntWitwer, KennethYáñez-Mó, MaríaYoun, HyewonZeidler, ReinhardGho, Yong Song
Source
Bioinformatics. 31(6)
Subject
Biomedical Research
Computational Biology
Database Management Systems
Databases
Factual
Exosomes
Extracellular Space
Humans
Software
User-Computer Interface
Mathematical Sciences
Biological Sciences
Information and Computing Sciences
Bioinformatics
Language
Abstract
MotivationExtracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for EV-related publications and vesicular components are currently challenging.ResultsWe present an improved version of EVpedia, a public database for EVs research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular components from 263 high-throughput datasets, and has been accessed more than 65 000 times from more than 750 cities. In addition, about 350 members from 73 international research groups have participated in developing EVpedia. This free web-based database might serve as a useful resource to stimulate the emerging field of EV research.Availability and implementationThe web site was implemented in PHP, Java, MySQL and Apache, and is freely available at http://evpedia.info.