학술논문

Using Serologic Testing to Assess the Effectiveness of Outbreak Control Efforts, Serial Polymerase Chain Reaction Testing, and Cohorting of Positive Severe Acute Respiratory Syndrome Coronavirus 2 Patients in a Skilled Nursing Facility
Document Type
article
Source
Clinical Infectious Diseases. 73(3)
Subject
Clinical Research
Pneumonia
Infectious Diseases
Lung
Pneumonia & Influenza
Health Services
Prevention
Emerging Infectious Diseases
Good Health and Well Being
COVID-19
Disease Outbreaks
Humans
Polymerase Chain Reaction
SARS-CoV-2
Skilled Nursing Facilities
SARS-CoV-2 serology
long-term care facility
infection control
Biological Sciences
Medical and Health Sciences
Microbiology
Language
Abstract
We characterized serology following a nursing home outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where residents were serially tested by reverse-transcription polymerase chain reaction (RT-PCR) and positive residents were cohorted. When tested 46-76 days later, 24 of 26 RT-PCR-positive residents were seropositive; none of the 124 RT-PCR-negative residents had confirmed seropositivity, supporting serial SARS-CoV-2 RT-PCR testing and cohorting in nursing homes.