학술논문
Genome-wide association study identifies 48 common genetic variants associated with handedness
Document Type
article
Author
Cuellar-Partida, Gabriel; Tung, Joyce Y; Eriksson, Nicholas; Albrecht, Eva; Aliev, Fazil; Andreassen, Ole A; Barroso, Inês; Beckmann, Jacques S; Boks, Marco P; Boomsma, Dorret I; Boyd, Heather A; Breteler, Monique MB; Campbell, Harry; Chasman, Daniel I; Cherkas, Lynn F; Davies, Gail; de Geus, Eco JC; Deary, Ian J; Deloukas, Panos; Dick, Danielle M; Duffy, David L; Eriksson, Johan G; Esko, Tõnu; Feenstra, Bjarke; Geller, Frank; Gieger, Christian; Giegling, Ina; Gordon, Scott D; Han, Jiali; Hansen, Thomas F; Hartmann, Annette M; Hayward, Caroline; Heikkilä, Kauko; Hicks, Andrew A; Hirschhorn, Joel N; Hottenga, Jouke-Jan; Huffman, Jennifer E; Hwang, Liang-Dar; Ikram, M Arfan; Kaprio, Jaakko; Kemp, John P; Khaw, Kay-Tee; Klopp, Norman; Konte, Bettina; Kutalik, Zoltan; Lahti, Jari; Li, Xin; Loos, Ruth JF; Luciano, Michelle; Magnusson, Sigurdur H; Mangino, Massimo; Marques-Vidal, Pedro; Martin, Nicholas G; McArdle, Wendy L; McCarthy, Mark I; Medina-Gomez, Carolina; Melbye, Mads; Melville, Scott A; Metspalu, Andres; Milani, Lili; Mooser, Vincent; Nelis, Mari; Nyholt, Dale R; O’Connell, Kevin S; Ophoff, Roel A; Palmer, Cameron; Palotie, Aarno; Palviainen, Teemu; Pare, Guillaume; Paternoster, Lavinia; Peltonen, Leena; Penninx, Brenda WJH; Polasek, Ozren; Pramstaller, Peter P; Prokopenko, Inga; Raikkonen, Katri; Ripatti, Samuli; Rivadeneira, Fernando; Rudan, Igor; Rujescu, Dan; Smit, Johannes H; Smith, George Davey; Smoller, Jordan W; Soranzo, Nicole; Spector, Tim D; Pourcain, Beate St; Starr, John M; Stefánsson, Hreinn; Steinberg, Stacy; Teder-Laving, Maris; Thorleifsson, Gudmar; Stefánsson, Kári; Timpson, Nicholas J; Uitterlinden, André G; van Duijn, Cornelia M; van Rooij, Frank JA; Vink, Jaqueline M; Vollenweider, Peter; Vuoksimaa, Eero; Waeber, Gérard
Source
Nature Human Behaviour. 5(1)
Subject
Language
Abstract
Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International Handedness Consortium, we conducted a genome-wide association meta-analysis of handedness (N = 1,766,671). We found 41 loci associated (P