학술논문
Postoperative Complications in the Ahmed Baerveldt Comparison Study During Five Years of Follow-up
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article
Author
Budenz, Donald L; Feuer, William J; Barton, Keith; Schiffman, Joyce; Costa, Vital P; Godfrey, David G; Buys, Yvonne M; Budenz, Donald; Gedde, Steven J; Sayyad, Fouad El; Herndon, Leon; Godfrey, David; Fellman, Ronald; Robinson, James; Dueker, David; Riedel, Patrick; Samuelson, Thomas; Puertas, Renata; Chew, Paul; Aquino, Cecilia; Solish, Alfred M; Buys, Yvonne; Trope, Graham; Brandt, James D; Lim, Michele; Law, Simon; Costa, Vital; Sarkisian, Steve; Chopra, Vikas; Francis, Brian; Meallet, Mario; Varma, Rohit; Netland, Peter; Salim, Sarwat; Feldman, Robert; Bell, Nicholas; Chen, Philip; Heuer, Dale; Singh, Kuldev; Wright, Martha; Schiffman, Joyce C; Shi, Wei; Ajuria, Luz; Silva, Yolanda
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Abstract
PurposeTo compare the late complications in the Ahmed Baerveldt Comparison Study during 5 years of follow-up.DesignMulticenter, prospective randomized clinical trial.Methodssetting: Sixteen international clinical centers.Study populationTwo hundred seventy-six subjects aged 18-85 years with previous intraocular surgery or refractory glaucoma with intraocular pressure of >18 mm Hg.InterventionsAhmed Glaucoma Valve FP7 or Baerveldt Glaucoma Implant BG 101-350.Main outcome measuresLate postoperative complications (beyond 3 months), reoperations for complications, and decreased vision from complications.ResultsLate complications developed in 56 subjects (46.8 ± 4.8 5-year cumulative % ± SE) in the Ahmed Glaucoma Valve group and 67 (56.3 ± 4.7 5-year cumulative % ± SE) in the Baerveldt Glaucoma Implant group (P = .082). The cumulative rates of serious complications were 15.9% and 24.7% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .034), although this was largely driven by subjects who had tube occlusions in the 2 groups (0.8% in the Ahmed Glaucoma Valve group and 5.7% in the Baerveldt Glaucoma Implant group, P = .037). Both groups had a relatively high incidence of persistent diplopia (12%) and corneal edema (20%), although half of the corneal edema cases were likely due to pre-existing causes other than the aqueous shunt. The incidence of tube erosion was 1% and 3% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .04).ConclusionsLong-term rates of vision-threatening complications and complications resulting in reoperation were higher in the Baerveldt Glaucoma Implant than in the Ahmed Glaucoma Valve group over 5 years of follow-up.