학술논문

Are sleep continuity disturbance and fatigue prodromal symptoms of cancer development?
Document Type
article
Source
Subject
Biomedical and Clinical Sciences
Clinical Research
Cancer
Behavioral and Social Science
Mental Health
Sleep Research
Prevention
Fatigue
Humans
Immunity
Innate
Inflammation
Neoplasms
Prodromal Symptoms
Prospective Studies
Severity of Illness Index
Sleep
Sleep Initiation and Maintenance Disorders
Sleep Wake Disorders
Wakefulness
Insomnia
Sleep Disturbance
Prodrome
Medical and Health Sciences
Neurology & Neurosurgery
Biomedical and clinical sciences
Language
Abstract
Sleep continuity disturbance (also known as insomnia) and fatigue are common complaints of individuals diagnosed with cancer. Traditionally, many have believed that sleep continuity disturbance and fatigue are caused, in large measure, by the impact of the cancer diagnosis and treatment. Recent prospective research suggests however, that sleep continuity disturbance and fatigue may actually precede a cancer diagnosis. We suggest that sleep continuity disturbance and fatigue may in fact represent prodromal symptoms of cancer. We review the current perspectives of this sequence of events and present a revised schematic that accounts for the role of biological, behavioural, and cognitive factors that contribute to the development and maintenance of sleep continuity disturbances in cancer patients. Monitoring emergent and unexplained patient-reported fatigue, sleepiness, and insomnia may serve as early warning signs of new onset cancer, providing opportunity for early detection and early intervention.