학술논문
Identification of circulating proteins associated with general cognitive function among middle-aged and older adults
Document Type
article
Author
Tin, Adrienne; Fohner, Alison E; Yang, Qiong; Brody, Jennifer A; Davies, Gail; Yao, Jie; Liu, Dan; Caro, Ilana; Lindbohm, Joni V; Duggan, Michael R; Meirelles, Osorio; Harris, Sarah E; Gudmundsdottir, Valborg; Taylor, Adele M; Henry, Albert; Beiser, Alexa S; Shojaie, Ali; Coors, Annabell; Fitzpatrick, Annette L; Langenberg, Claudia; Satizabal, Claudia L; Sitlani, Colleen M; Wheeler, Eleanor; Tucker-Drob, Elliot M; Bressler, Jan; Coresh, Josef; Bis, Joshua C; Candia, Julián; Jennings, Lori L; Pietzner, Maik; Lathrop, Mark; Lopez, Oscar L; Redmond, Paul; Gerszten, Robert E; Rich, Stephen S; Heckbert, Susan R; Austin, Thomas R; Hughes, Timothy M; Tanaka, Toshiko; Emilsson, Valur; Vasan, Ramachandran S; Guo, Xiuqing; Zhu, Yineng; Tzourio, Christophe; Rotter, Jerome I; Walker, Keenan A; Ferrucci, Luigi; Kivimäki, Mika; Breteler, Monique MB; Cox, Simon R; Debette, Stephanie; Mosley, Thomas H; Gudnason, Vilmundur G; Launer, Lenore J; Psaty, Bruce M; Seshadri, Sudha; Fornage, Myriam
Source
Communications Biology. 6(1)
Subject
Language
Abstract
Identifying circulating proteins associated with cognitive function may point to biomarkers and molecular process of cognitive impairment. Few studies have investigated the association between circulating proteins and cognitive function. We identify 246 protein measures quantified by the SomaScan assay as associated with cognitive function (p