학술논문

The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018
Document Type
article
Source
Journal for ImmunoTherapy of Cancer. 7(1)
Subject
Biomedical and Clinical Sciences
Oncology and Carcinogenesis
Immunology
Immunization
Vaccine Related
Cancer
Development of treatments and therapeutic interventions
5.1 Pharmaceuticals
Good Health and Well Being
History
21st Century
Humans
Immunotherapy
Anti-CTLA-4
Anti-PD-1
Combination therapy
Immunity
Treatment resistance
Oncology and carcinogenesis
Language
Abstract
As part of the 2018 Immunotherapy Bridge congress (November 28-29, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on four topical clinical issues in immunotherapy today. These were: the relative importance of adaptive versus innate immunity in the anti-cancer immune response; the merits of combination versus sequential immunotherapy regimens in the treatment of cancer; the advantages and disadvantages of murine models of cancer versus humans in order to evaluate immunotherapy; and whether or not mechanisms of resistance to immunotherapy differ between different cancers. Discussion of these important topics are summarised in this report.