학술논문

A genome assembly of the Yuma myotis bat, Myotis yumanensis
Document Type
article
Source
Journal of Heredity. 115(1)
Subject
Biological Sciences
Bioinformatics and Computational Biology
Genetics
Biotechnology
Human Genome
Animals
Chiroptera
North America
Genome
Genomics
Biological Evolution
California Conservation Genomics Project
CCGP
chiroptera
long-read assembly
Myotis yumanensis
reference genome
Evolutionary Biology
Evolutionary biology
Language
Abstract
The Yuma myotis bat (Myotis yumanensis) is a small vespertilionid bat and one of 52 species of new world Myotis bats in the subgenus Pizonyx. While M. yumanensis populations currently appear relatively stable, it is one of 12 bat species known or suspected to be susceptible to white-nose syndrome, the fungal disease causing declines in bat populations across North America. Only two of these 12 species have genome resources available, which limits the ability of resource managers to use genomic techniques to track the responses of bat populations to white-nose syndrome generally. Here we present the first de novo genome assembly for Yuma myotis, generated as a part of the California Conservation Genomics Project. The M. yumanensis genome was generated using a combination of PacBio HiFi long reads and Omni-C chromatin-proximity sequencing technology. This high-quality genome is one of the most complete bat assemblies available, with a contig N50 of 28.03 Mb, scaffold N50 of 99.14 Mb, and BUSCO completeness score of 93.7%. The Yuma myotis genome provides a high-quality resource that will aid in comparative genomic and evolutionary studies, as well as inform conservation management related to white-nose syndrome.