학술논문

Menopausal hormone therapy trends before versus after 2002
Document Type
article
Source
Menopause The Journal of The North American Menopause Society, vol Publish Ahead of Print, iss &NA
Subject
Biomedical and Clinical Sciences
Clinical Sciences
Health Sciences
Aging
Estrogen
Adult
Cohort Studies
Estrogen Replacement Therapy
Female
Hot Flashes
Humans
Logistic Models
Longitudinal Studies
Menopause
Middle Aged
Patient Compliance
Prospective Studies
Surveys and Questionnaires
United States
Women's Health
Hormone therapy
Vasomotor symptoms
Women's Health Initiative
Medical and Health Sciences
Obstetrics & Reproductive Medicine
Biomedical and clinical sciences
Health sciences
Psychology
Language
Abstract
ObjectiveTo better understand how to educate patients and providers about study findings relevant to treatment guidelines, we assessed pre- versus post-Women's Health Initiative (WHI) differences in menopausal hormone therapy (MHT) initiation and continuation and their correlates, and in women's reasons for initiation and discontinuation.MethodsWe analyzed survey data from up to 14 approximately annual visits over 17 years (1996-2013) from 3,018 participants in the Study of Women's Health Across the Nation, a prospective cohort study. We used logistic regression to compare pre- versus post-WHI associations of covariates with MHT initiation and continuation, and to compare pre- versus post-WHI reasons for initiation and continuation.ResultsMHT initiation dropped from 8.6% pre-WHI to 2.8% post-WHI (P