학술논문

Population-based biomarker screening and the development of severe preeclampsia in California
Document Type
article
Source
American Journal of Obstetrics and Gynecology. 211(4)
Subject
Paediatrics and Reproductive Medicine
Obstetrics & Reproductive Medicine
Language
Abstract
Objective The purpose of this study was to examine the relationship between second-trimester maternal serum biomarkers and the development of early- and late-onset severe preeclampsia in euploid pregnancies. Study Design Included were 136,139 pregnancies that obtained second-trimester prenatal screening through the California Prenatal Screening Program with live births in 2006-2008. We identified severe preeclampsia diagnoses from hospital discharge records. We used log binomial regression to examine the association between abnormal second-trimester maternal serum biomarkers and the development of severe preeclampsia.