학술논문
Vitamin D3 Supplementation Increases Spine Bone Mineral Density in Adolescents and Young Adults With Human Immunodeficiency Virus Infection Being Treated With Tenofovir Disoproxil Fumarate: A Randomized, Placebo-Controlled Trial
Document Type
article
Author
Havens, Peter L; Stephensen, Charles B; Van Loan, Marta D; Schuster, Gertrud U; Woodhouse, Leslie R; Flynn, Patricia M; Gordon, Catherine M; Pan, Cynthia G; Rutledge, Brandy; Harris, D Robert; Price, Georgine; Baker, Alyne; Meyer, William A; Wilson, Craig M; Hazra, Rohan; Kapogiannis, Bill G; Mulligan, Kathleen; Vellala, Kavya; Wheeler, Justin; Fielding, Roger; Freytag, Tammy; Domek, Joseph; Gertz, Erik; Emmanuel, Patricia; Straub, Diane; Enriquez-Bruce, Elizabeth; Belzer, Marvin; Tucker, Diane; D’Angelo, Larry; Trexler, Connie; Douglas, Steve; Tanney, Mary; Stroger, John H; Martinez, Miguel; Henry-Reid, Lisa; Bojan, Kelly; Futterman, Donna; Campos, Maria; Abdalian, Sue Ellen; Kozina, Leslie; Friedman, Larry; Maturo, Donna; Flynn, Pat; Guar, Aditya; Dillard, Mary; Paul, Mary; Head, Jane; Secord, Liz; Outlaw, Angulique; Cromer, Charnell; Agwu, Allison; Sanders, Renata; Anderson, Thuy; Mayer, Ken; Dormitzer, Julian; Reirden, Dan; Chambers, Carrie; Kovacs, Andrea; Operskalski, Eva; Homans, James; Bearden, Allison; Sanchez, Susie; Puga, Ana; Eysallenne, Zulma; Acevedo, Midnela; Rosario, Nicolas; Nieves, Lourdes Angeli; Wiznia, Andrew; Abadi, Jacobo; Rosenberg, Michael; Dobroszycki, Joanna; Burey, Marlene
Source
Clinical Infectious Diseases. 66(2)
Subject
Language
Abstract
BackgroundTenofovir disoproxil fumarate (TDF) decreases bone mineral density (BMD). We hypothesized that vitamin D3 (VITD3) would increase BMD in youth receiving TDF.MethodsThis was a randomized, double-blind, placebo-controlled trial of directly observed VITD3 vs placebo every 4 weeks for 48 weeks in youth aged 16-24 years with HIV, RNA load