학술논문
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes
Document Type
article
Author
Robertson, Catherine C; Inshaw, Jamie RJ; Onengut-Gumuscu, Suna; Chen, Wei-Min; Santa Cruz, David Flores; Yang, Hanzhi; Cutler, Antony J; Crouch, Daniel JM; Farber, Emily; Bridges, S Louis; Edberg, Jeffrey C; Kimberly, Robert P; Buckner, Jane H; Deloukas, Panos; Divers, Jasmin; Dabelea, Dana; Lawrence, Jean M; Marcovina, Santica; Shah, Amy S; Greenbaum, Carla J; Atkinson, Mark A; Gregersen, Peter K; Oksenberg, Jorge R; Pociot, Flemming; Rewers, Marian J; Steck, Andrea K; Dunger, David B; Wicker, Linda S; Concannon, Patrick; Todd, John A; Rich, Stephen S
Source
Nature Genetics. 53(7)
Subject
Language
Abstract
We report the largest and most diverse genetic study of type 1 diabetes (T1D) to date (61,427 participants), yielding 78 genome-wide-significant (P