학술논문
The return of quiescence metabolites
Document Type
article
Author
Source
Nature Cell Biology. 23(4)
Subject
Language
Abstract
The transition of endothelial cells between quiescence and proliferation is essential for regulating the extent of the vasculature that supplies oxygen and nutrients to tissues. A study now shows that the FOXO1 transcription factor regulates endothelial cell proliferation by controlling levels of the metabolite 2-hydroxyglutarate.