학술논문
Randomized Trial of a “Dynamic Choice” Patient-Centered Care Intervention for Mobile Persons With HIV in East Africa
Document Type
article
Author
Ayieko, James; Balzer, Laura B; Inviolata, Colette; Kakande, Elijah; Opel, Fred; Wafula, Erick M; Kabami, Jane; Owaraganise, Asiphas; Mwangwa, Florence; Nakato, Hellen; Bukusi, Elizabeth A; Camlin, Carol S; Charlebois, Edwin D; Bacon, Melanie C; Petersen, Maya L; Kamya, Moses R; Havlir, Diane V; Chamie, Gabriel; Team, SEARCH Study
Source
JAIDS Journal of Acquired Immune Deficiency Syndromes. 95(1)
Subject
Language
Abstract
BackgroundPersons with HIV (PWH) with high mobility face obstacles to HIV care engagement and viral suppression. We sought to understand whether a patient-centered intervention for mobile PWH would improve viral suppression and retention in care, and if so, which subgroups would benefit most.MethodsIn a randomized trial, we evaluated the effect of an intervention designed to address barriers to care among mobile (≥2 weeks out of community in previous year) PWH with viral nonsuppression or recent missed visits in Kenya and Uganda (NCT04810650). The intervention included dynamic choice of a "travel pack" (emergency antiretroviral therapy [ART] supply, discrete ART packaging, and travel checklist), multimonth and offsite refills, facilitated transfer to out-of-community clinics, and hotline access to a mobility coordinator. The primary outcome was viral suppression (