학술논문

Transgender Women Living with HIV Frequently Take Antiretroviral Therapy and/or Feminizing Hormone Therapy Differently Than Prescribed Due to Drug–Drug Interaction Concerns
Document Type
article
Source
LGBT Health. 4(5)
Subject
Health Services and Systems
Policy and Administration
Health Sciences
Human Society
Infectious Diseases
Clinical Research
HIV/AIDS
Evaluation of treatments and therapeutic interventions
6.1 Pharmaceuticals
Infection
Anti-HIV Agents
Cross-Sectional Studies
Drug Interactions
Female
HIV Infections
Hormone Replacement Therapy
Humans
Los Angeles
Male
Medication Adherence
Middle Aged
Pilot Projects
Transgender Persons
antiretroviral therapy
health disparities
HIV
medication adherence
transgender
Health services and systems
Policy and administration
Language
Abstract
PurposeBoth hormone therapy (HT) and antiretroviral therapy (ART) can be lifesaving for transgender women (TW) living with HIV, but each has side effects and potential drug-drug interactions (DDI). We assessed how concerns about HT-ART interactions affect treatment adherence.MethodsThis study used a cross-sectional survey of TW (n = 87) in Los Angeles, CA.ResultsFifty-four percent were living with HIV; 64% used HT. Only 49% of TW living with HIV discussed ART-HT DDI with their provider; 40% reported not taking ART (12%), HT (12%), or both (16%) as directed due to DDI concerns.ConclusionImperfect HT/ART use and limited provider communication suggests a need for improved HT-ART integration.