학술논문

What’s next for cancer vaccines
Document Type
article
Source
Science Translational Medicine. 14(670)
Subject
Biomedical and Clinical Sciences
Oncology and Carcinogenesis
Immunology
Rare Diseases
Biotechnology
Cancer
Orphan Drug
Prevention
Vaccine Related
Immunization
3.4 Vaccines
6.1 Pharmaceuticals
Prevention of disease and conditions
and promotion of well-being
Evaluation of treatments and therapeutic interventions
Good Health and Well Being
Humans
Cancer Vaccines
Immunotherapy
Neoplasms
Biological Sciences
Medical and Health Sciences
Medical biotechnology
Biomedical engineering
Language
Abstract
Cancer vaccines have been shown clinically to drive tumor-reactive cell activation, proliferation, and effector function. Unfortunately, tumor eradication by treatment with cancer vaccines has been unsuccessful in many patients. Critical steps are under way to improve vaccine efficacy and combine them with immunotherapy and standard-of-care treatments.