학술논문

Aggregation-Induced Emission (AIE), Life and Health.
Document Type
article
Source
ACS Nano. 17(15)
Subject
aggregation-induced emission
bioimaging
biomedical application
combined therapy
detection
luminescent material
monitoring
phototheranostics
precision medicine
Fluorescent Dyes
Luminescent Agents
Luminescence
Diagnostic Imaging
Delivery of Health Care
Language
Abstract
Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents and imaging techniques currently being used to assess health and treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) has shown great potential in biological applications due to its advantages in terms of brightness, biocompatibility, photostability, and positive correlation with concentration. This review provides a comprehensive summary of AIE luminogens applied in imaging of biological structure and dynamic physiological processes, disease diagnosis and treatment, and detection and monitoring of specific analytes, followed by representative works. Discussions on critical issues and perspectives on future directions are also included. This review aims to stimulate the interest of researchers from different fields, including chemistry, biology, materials science, medicine, etc., thus promoting the development of AIE in the fields of life and health.