학술논문

Severe bilateral optic nerve and retinal hypoperfusion in a patient with acute respiratory distress syndrome and septic shock
Document Type
article
Source
Subject
Biomedical and Clinical Sciences
Ophthalmology and Optometry
Hematology
Neurosciences
Neurodegenerative
Eye Disease and Disorders of Vision
Peripheral Neuropathy
Cardiovascular
Eye
Acute respiratory distress syndrome
Central retinal artery occlusion
Diffusion-weighted magnetic resonance imaging
Ischemic optic neuropathy
Septic shock
Language
Abstract
PurposeTo report a case of bilateral central retinal artery occlusion with both anterior and posterior ischemic optic neuropathy.ObservationsA 65-year-old Caucasian woman presented with acute respiratory distress syndrome and septic shock. After treatment with vasopressors and prolonged prone positioning, she was noted to be bilaterally completely blind on hospitalization day 12. Evaluation revealed evidence of bilateral central retinal artery occlusion and bilateral ischemic optic neuropathy. Magnetic resonance imaging of the orbits demonstrated severe restricted diffusion of both optic nerves consistent with ischemia. Both central retinal artery occlusion and ischemic optic neuropathy have been reported in cases of severe hypotension, blood loss, and prone positioning, most often postoperatively after spinal surgery.Conclusions and importanceTo our knowledge, this is the first reported case of bilateral central retinal artery occlusion with both anterior and posterior ischemic optic neuropathy, presumed due to the combination of severe systemic hypotension, hypoxemia due to the respiratory distress syndrome, and prolonged prone positioning.