학술논문

Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet?
Document Type
article
Source
Journal of Allergy and Clinical Immunology. 137(4)
Subject
Biomedical and Clinical Sciences
Immunology
Nutrition
Foodborne Illness
Food Allergies
Digestive Diseases
Allergens
Cross Reactions
Eosinophilic Esophagitis
Food Hypersensitivity
Glutens
Hordeum
Humans
Secale
Triticum
Eosinophilic esophagitis
6-food elimination diet
wheat
cross-reactivity
gluten
Allergy
Language
Abstract
Eosinophilic esophagitis (EoE), a food antigen-mediated disease, is effectively treated with the dietary elimination of 6 foods commonly associated with food allergies (milk, wheat, egg, soy, tree nuts/peanuts, and fish/shellfish). Because wheat shares homologous proteins (including gluten) with barley and rye and can also be processed with these grains, some clinicians have suggested that barley and rye might also trigger EoE as a result of cross-reaction and/or cross-contamination with wheat. In this article, we discuss the theoretical risks of cross-reactivity and cross-contamination among wheat, barley, and rye proteins (including gluten); assess common practices at EoE treatment centers; and provide recommendations for dietary treatment and future studies of EoE.