학술논문
ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
Document Type
redif-article
Author
Source
Nature, Nature. 543(7644):265-269
Subject
Language
English
Abstract
The chromatin-reader protein ENL regulates oncogenic programs in acute myeloid leukaemia by binding via its YEATS domain to acetylated histones on the promoters of actively transcribed genes and recruiting the transcriptional machinery.