학술논문
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus
Document Type
redif-article
Author
Source
Nature, Nature. 527(7576):114-117
Subject
Language
English
Abstract
The X-ray crystal structure of influenza C virus polymerase, captured in a closed, pre-activation confirmation, is solved at 3.9 Å resolution; comparison with previous RNA-bound structures reveals large conformational changes associated with RNA binding and activation, and illustrates the notable flexibility of the influenza virus RNA polymerase.