학술논문
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
Document Type
redif-article
Author
Source
Nature, Nature. 551(7682):639-643
Subject
Language
English
Abstract
Cancers growing in high-oxygen environments, such as lung adenocarcinomas, select for the iron–sulfur cluster synthesizing enzyme NFS1 to support malignant proliferation and to protect from oxidative damage.