학술논문
Sensory-evoked LTP driven by dendritic plateau potentials in vivo
Document Type
redif-article
Author
Source
Nature, Nature. 515(7525):116-119
Subject
Language
English
Abstract
Whole-cell recordings in mouse somatosensory cortex in vivo show that rhythmic sensory-whisker stimulation induces long-term synaptic potentiation (LTP) in layer 2/3 (L2/3) pyramidal cells, in the absence of somatic spikes, through long-lasting NMDAR-mediated depolarizations that are generated by synaptic networks originating from the posteromedial complex of the thalamus.