부산대학교 도서관

Given the increasing importance of Platichthys stellatus in the aquaculture industry, basic research on the immune response is needed. Therefore, we analyzed the molecular biology and expression of the Nuclear factor interleukin 3 regulated protein (NFIL3) gene, which plays an important role in innate immunity. Tissue-specific expression analysis of healthy P. stellatus showed that NFIL3 mRNA had the highest expression in gill, followed by skin and trunk kidney. In the Viral Hemorrhagic Septicemia Virus (VHSV) infection group, the tissues that were significantly expressed after infection were the trunk kidney, spleen, gills, and heart, and the strongest expression was observed in the trunk kidney. In the Streptococcus parauberis PH0710 infection group, high expression was observed in the liver on day 1, and in the intestine and brain on day 7.