학술논문

3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene, A New Phenanthrene from Bulbophyllum Odoratissimum
Document Type
Academic Journal
Source
대한화학회지. 2007-08 51(4):352-355
Subject
3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene
난초목난초과
세포독성
페난트렌
Bulbophyllum odoratissimum
Cytotoxicity
Orchidaceae
Phenanthrene
Language
Korean
ISSN
1017-2548
2234-8530
Abstract
A new phenanthrene derivative 3,7-dihydroxy-2,4,6-trimethoxyphenanthrene was isolated from the all plant of Bulbophyllum odoratissimum, and its structure was elucidated by extensive spectral studies and chemical transformation. The compound displayed cytotoxicity against the growth of human leukemia cell lines K562 and HL-60, human lung adenocarcinoma A549, human hepatoma BEL-7402 and human stomach cancer cell lines SGC-7901 with IC50 values of 14.23, 10.02, 3.42, 15.36 and 1.13 mg/ml respectively.