부산대학교 도서관

In nephrological pathology, incidence of bacteria is mainly correlated with the increased use of central or peripheral venous catheters, which is unavoidable in hemodialysis. The aim of this study is to determine bacteriological etiologies of bacteremia among hemodialysis patients between January and December 2021 and to determine their antibiotics susceptibility profiles. Blood culture balloons received from the Nephrology Department were immediately incubated in the Bactec FX 40. With the detection of an alarm due to growing suspicion of microorganisms, identification of the suspected germ and antimicrobial susceptibility testing were performed. 37 (53%) blood cultures were positive with a predominance in women (54%). Gram negative bacteria was most isolated in bacteremia with 59% rate. Among bacteria responsible of bacteremia, Staphylococcus aureus (n=13; 36%), Enterobacter cloacae (n=8; 22%), Escherichia coli (n=6; 16%) and Klebsiella pneumoniae (n=4; 11%) were most important. Regarding antibiotics susceptibility of bacteria, oxacillin (83%), tobramycin (92%), gentamycin (100%) and vancomycin (100%) were most active in S. aureus. For E. cloacae, cefepim (88%), cefixim (75%), tobramycin (88%), imipenem (100%) and tigecyclin (100%) were most active. Regarding of E. coli, imipenem (100%), ceftazidim (83%), cefoxitin (83%), amikacin (100%) and gentamicin (83%) were most active. In conclusion, this study shows the high rate of bacteremia in nephrology department of CHNU Aristide Le Dantec with antibiotics more or less active.