학술논문

Studies on Some Bioactive 1,1-Bis(2-benzylidene-5-aryliden-1,3-thiadiazolidin-4-one)cyclopropane
Document Type
Academic Journal
Source
대한화학회지. 2011-12 55(6):994-999
Subject
Acute toxicity
Antibacterial
Antifungal
Bis-phenylarylidinylthiadiazolidinone cyclopropane
Language
Korean
ISSN
1017-2548
2234-8530
Abstract
Some novel heterocyclic derivatives of 1,1-bis(2-phenyl-5-arylidine-1,3-thiadiazolidin-4-one)cyclopropane 4(a-i) have been synthesized from cyclopropane dicarboxylic acid and substituted thiadiazole moieties. All the synthesized compounds have been characterized by elemental and spectral (I.R., -NMR, Mass) analysis. Furthermore, above said compounds were screened for their antifungal and antibacterial activities. Compound 4c was found the most potent one which further evaluated for lesser toxicity test.