학술논문
Synthesis of carbamoylpyridone HIV integrase inhibitors and intermediates
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Patent
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Abstract
A synthesis approach providing an early ring attachment via a bromination to compound I-I yielding compound II-II: [chemical expression included] whereby a final product such as AA: [chemical expression included] can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q.