학술논문
Compounds useful for inhibition of farnesyl protein transferase
Document Type
Patent
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Abstract
Novel compounds of the formula: ##STR1##
are disclosed. Compounds of Formula 1.0 are represented by the compounds of formulas: ##STR2##
wherein R.sup.1, R.sup.3 and R.sup.4 are each independently selected from halo. Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells.
are disclosed. Compounds of Formula 1.0 are represented by the compounds of formulas: ##STR2##
wherein R.sup.1, R.sup.3 and R.sup.4 are each independently selected from halo. Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells.