학술논문
Amyloid beta receptor and uses thereof
Document Type
Patent
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Abstract
The present invention relates to the identification that soluble assemblies of amyloid β function as a NMDA receptor antagonist. The present invention also provides methods and compositions for the detection and treatment of neurodegenerative and cognitive disorders and screening methods to identify agents that modulate the antagonistic effect of soluble assemblies of amyloid β on NMDA receptor function.