학술논문

HoPaCI-DB: host-Pseudomonas and Coxiella interaction database
Document Type
Academic Journal
Source
Nucleic Acids Research. Jan 01, 2014 42(D1):D671-D676
Subject
Language
English
ISSN
0305-1048
Abstract
Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenchen.de/HoPaCI/) of host–pathogen interaction data from Pseudomonas aeruginosa and Coxiella burnetii. The resource provides structured information on 3585 experimentally validated interactions between molecules, bioprocesses and cellular structures extracted from the scientific literature. Systematic annotation and interactive graphical representation of disease networks make HoPaCI-DB a versatile knowledge base for biologists and network biology approaches.