학술논문
EFFECT OF AUTOLOGOUS PLATELET ADHESIVES ON DERMAL FAT GRAFT RESORPTION FOLLOWING RECONSTRUCTION OF A SUPERFICIAL PAROTIDECTOMY DEFECT: A DOUBLE-BLINDED PROSPECTIVE TRIAL
Document Type
Academic Journal
Author
Source
Head & Neck. Apr 01, 2009 31(4):521-530
Subject
Language
English
ISSN
1043-3074
Abstract
BACKGROUND.: Dermal fat grafts are used to reconstruct facial contour defects but may undergo variable resorption. Application of autologous platelet adhesive may improve outcomes. The primary objective was to compare resorption of dermal fat grafts for parotidectomy defects, between patients receiving autologous platelet adhesive versus controls. METHODS.: This was a double-blinded prospective cohort at a tertiary care center. Volumetric analyses of dermal fat graft measured by MRI scans. Resorption was determined by comparing 1- and 6-month MRIs in each patient. Complications, Freyʼs Syndrome, and patient satisfaction were also assessed. RESULTS.: Twelve patients completed the study. A significant reduction in graft resorption was seen in the treatment group (57% vs. 31%, p = .01). Three patients in the control group developed fat liquefaction. Patient perceived significant differences in scar and contour. CONCLUSION.: Application of autologous platelet adhesives improved graft viability and patient satisfaction at 6 months. © 2009 Wiley Periodicals, Inc. Head Neck, 2009