학술논문
Vitamin D deficiency and changes in serum vitamin D levels with treatment among tuberculosis patients in South Korea
Document Type
Academic Journal
Author
Source
Respirology. Jul 01, 2012 17(5):808-813
Subject
Language
English
ISSN
1323-7799
Abstract
BACKGROUND AND OBJECTIVE:: METHODS:: RESULTS:: In total, 116 patients with TB and 86 control subjects were recruited. The median 25-OHD concentration was not different in TB patients at diagnosis (13.9 ng/mL; interquartile range (IQR) 8.80–21.8) compared with control subjects (13.2 ng/mL; IQR 9.6–19.3) ( P = 0.97). The frequency of vitamin D deficiency (≤10 ng/mL) was also not different in TB patients (36.2%) compared with controls (27.3%) ( P = 0.21). In TB patients, the median 25-OHD concentration decreased significantly during treatment, to 12.5 ng/mL at 1 month and 11.0 ng/mL on completion of treatment ( P = 0.01). CONCLUSIONS