학술논문
The Effect of Carbetocin Dose on Transmural Dispersion of Myocardial Repolarization in Healthy Parturients Scheduled for Elective Cesarean Delivery Under Spinal Anesthesia: A Prospective, Randomized Clinical Trial
Document Type
Academic Journal
Author
Source
Obstetric Anesthesia Digest. Sep 01, 2021 41(3):132-133
Subject
Language
English
ISSN
0275-665X
Abstract
(Anesth Analg. 2021;132:485–492)Transmural dispersion of myocardial repolarization (TDR) is the interval between the peak of the T wave and end of the TV wave (Tp-e). Increased TDR is a more reliable predictor of drug torsadogenicity than prolonged QT interval. Carbetocin, a synthetic analog of oxytocin, is used to prevent postpartum hemorrhage following cesarean delivery, though the effect dose varies. Carbetocin has been shown to increase mean correct QT, but there is a paucity of information on the effects of carbetocin of TDR. This study examined the effects of carbetocin dose on TDR in patients undergoing cesarean delivery under spinal anesthesia.