학술논문
Association of Antepartum and Postpartum Depression in Ghanaian and Ivorian Women With Febrile Illness in Their Offspring: A Prospective Birth Cohort Study
Document Type
Academic Journal
Author
Guo, Nan; Bindt, Carola; Te Bonle, Marguerite; Appiah-Poku, John; Hinz, Rebecca; Barthel, Dana; Koffi, Mathurin; Posdzich, Sarah; Deymann, Simon; Barkmann, Claus; Schlüter, Lisa; Jaeger, Anna; Blay Nguah, Samuel; Eberhardt, Kirsten A.; NʼGoran, Eliezer; Tagbor, Harry; Ehrhardt, Stephan; Baum, Jana; Burchard, Gerd D.; Claussen, Lisa; Ewert, Heike; Feldt, Torsten; Fordjour, Daniel; Hahn, Andreas; Koffi, Jean E.; Kra, Esther; Loag, Wibke; May, Jürgen; Mohammed, Yasmin; Osei, Yaw; Reime, Birgit; Schoppen, Stefanie; Tannich, Egbert
Source
American Journal of Epidemiology. Nov 01, 2013 178(9):1394-1402
Subject
Language
English
ISSN
0002-9262
Abstract
In low-income countries, perinatal depression is common, but longitudinal data on its influence on child health are rare. We examined the association between maternal depression and febrile illness in children. There were 654 mother/child dyads in Ghana and Côte dʼIvoire that were enrolled in a prospective birth cohort in 2010–2011 and underwent 2-years of follow up. Mothers were examined for depression using the Patient Health Questionnaire depression module antepartum and 3 and 12 months postpartum. The hazard of febrile illness in children of depressed and nondepressed mothers was estimated using a recurrent event Cox proportional hazards model. The prevalences of antepartum depression in mothers from Côte dʼIvoire and Ghana were 28.3% and 26.3%, respectively. The prevalences of depression at 3 and 12 months postpartum were 11.8% and 16.1% (Côte dʼIvoire) and 8.9% and 7.2% (Ghana). The crude and adjusted (for country and socioeconomic status) hazard ratios of febrile illness in children of depressed mothers compared with those in children of nondepressed mothers were 1.57 (95% confidence interval: 1.20, 2.07) and 1.32 (95% confidence interval: 1.01, 1.74) respectively. Perinatal depression was frequent and associated with febrile illness in the offspring. Our results showed that a high prevalence of depression in sub-Saharan Africa may pose a serious public health threat to women and their offspring.