학술논문
The value of EEG-fMRI and EEG source analysis in the presurgical setup of children with refractory focal epilepsy
Document Type
Academic Journal
Author
Source
Epilepsia. Sep 01, 2012 53(9):1597-1606
Subject
Language
English
ISSN
0013-9580
Abstract
PURPOSE:: METHODS:: Simultaneous EEG-fMRI was recorded in nine patients (ages 1.5–17.5 years) undergoing presurgical evaluation. The postoperative outcome and resected area were compared with the following: the localizations of blood oxygen–level dependent (BOLD) signal changes associated with IEDs, which were identified by visual inspection changes using SPM5 software (Analysis I); BOLD signal changes related to IED topography, which was characterized using spike-specific voltage maps of average IED recorded outside the MR scanner during clinical long-term monitoring (Analysis II); as well as results of EEG source analysis based on the distributed linear local autoregressive average (LAURA) algorithm using the Cartool software by Denis Brunet (Analysis III). KEY FINDINGS:: CONCLUSIONS