학술논문
Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe
Document Type
Academic Journal
Author
Malik, Farihah; Crichton, Siobhan; Plotnikova, Yulia; Latysheva, Inga; Samarina, Anna; Pokorska-Śpiewak, Maria; Gomez, Marisa Navarro; Bailey, Heather; Thorne, Claire; Judd, Ali; Turkova, Anna; Collins, Intira Jeannie; Marczyńska, Magdalena; Popielska, Jolanta; Ołdakowska, Agnieszka; Zawadka, Konrad; Pluta, Magdalena; Doroba, Małgorzata; Okhonskaya, Liubov; Rozenberg, Vladimir; Voronin, Evgeny; Plynsky, Alexksey A.; José Mellado, María; Escosa, Luis; García Hortelano, Milagros; Sainz, Talía; Grasa, Carlos; Rodríguez, Paula; Rojo, Pablo; Prieto-Tato, Luis; Epalza, Cristina; Tagarro, Alfredo; Domínguez, Sara; Ballesteros, Álvaro; Tomás Ramos, José; Illán, Marta; Berzosa, Arantxa; Guillén, Sara; Soto, Beatriz; Luisa Navarro, María; Saavedra, Jesús; Santos, Mar; Aguilera, David; Santiago, Begoña; Jimenez de Ory, Santiago; Bermejo, Amanda; Penín, María; Martínez, Jorge; Badillo, Katie; Belén Jiménez, Ana; Navas, Adriana; Oñate, Eider; Pocheville, Itziar; Garrote, Elisa; Colino, Elena; Afonso, Olga; Gómez Sirvent, Jorge; Garzón, Mónica; Román, Vicente; Angulo, Raquel; Neth, Olaf; Falcón, Lola; Terol, Pedro; Luis Santos, Juan; Vázquez, Álvaro; Carazo, Begoña; Medina, Antonio; Lendínez, Francisco; Ibáñez, Mercedes; Peromingo, Estrella; Isabel Sánchez, María; Ruiz, Beatriz; Grande, Ana; José Romero, Francisco; Pérez, Carlos; Calle, Laura; Pareja, Marta; Losada, Begoña; Herranz, Mercedes; Bustillo, Matilde; Collado, Pilar; Antonio Couceiro, José; Vila, Leticia; Calviño, Consuelo; Isabel Piqueras, Ana; Oltra, Manuel; Gavilán, César; Montesinos, Elena; Dapena, Marta; Jiménez, Beatriz; Gloria Andrés, Ana; Marugán, Víctor; Ochoa, Carlos; Isabel Menasalvas, Ana; Cervantes, Eloísa; Álvarez, Beatriz; Díez, Cristina; Bernardino, Ignacio; Luisa Montes, María; Valencia, Eulalia; Delgado, Ana; Rubio, Rafael; Pulido, Federico; Bisbal, Otilia; Monereo Alonso, Alfonso; Berenguer, Juan; Díez, Cristina; Aldamiz, Teresa; Tejerina, Francisco; Carlos Bernaldo de Quirós, Juan; Padilla, Belén; Carrillo, Raquel; Montilla, Pedro; Bermúdez, Elena; Valerio, Maricela; Sanz, Jose; Gimeno, Alejandra; Cervero, Miguel; Torres, Rafael; Moreno, Santiago; Jesús Perez, María; del Campo, Santos; Ryan, Pablo; Troya, Jesus; Sanz, Jesus; Losa, Juan; Gomez, Rafael; Górgolas, Miguel; Díaz, Alberto; de la Fuente, Sara; Antonio Iribarren, Jose; Jose Aramburu, Maria; Martinez, Lourdes; Josune Goikoetxea, Ane; Ibarra, Sofia; de la Peña, Mireia; Asensi, Víctor; Hernandez, Michele; Remedios Alemán, María; Pelazas, Ricardo; del Mar Alonso, María; María López, Ana; García, Dácil; Rodriguez, Jehovana; Angel Cardenes, Miguel; Castaño, Manuel A.; Orihuela, Francisco; Pérez, Inés; Isabel Mayorga, Mª; Fernando Lopez-Cortes, Luis; Roca, Cristina; Llaves, Silvia; Jose Rios, Maria; Rodriguez, Jesus; Palomo, Virginia; Pasquau, Juan; Garcia, Coral; Hernandez, Jose; Martinez, Clara; Rivero, Antonio; Camacho, Angela; Merino, Dolores; Raffo, Miguel; Corpa, Laura; Martinez, Elisa; Mateos, Fernando; Javier Blanch, Jose; Torralba, Miguel; Arazo, Piedad; Samperiz, Gloria; Miralles, Celia; Ocampo, Antonio; Pousada, Guille; Mena, Alvaro; Montero, Marta; Salavert, Miguel; Jose Galindo, Maria; Pretel, Natalia; Portilla, Joaquín; Portilla, Irene; Gutierrez, Felix; Masia, Mar; Robledano, Cati; Adsuar, Araceli; Hinojosa, Carmen; Monteagudo, Begoña; Bachiller, Pablo; Abadía, Jesica; Galera, Carlos; Albendin, Helena; Fernandez, Marian; Ramon Blanco, Jose
Source
The Pediatric Infectious Disease Journal. May 01, 2024 43(5):e155-e159
Subject
Language
English
ISSN
0891-3668
Abstract
We evaluated the effectiveness and safety of direct-acting antivirals in adolescents with hepatitis C (HCV)/HIV coinfection using pooled individual patient-level data from 5 European cohorts. Of 122 participants in follow-up from November 2013 to August 2021, 19 were treated <18 years of age; of 15 with HCV RNA available at/after 12 weeks post-treatment, all had sustained virologic response with acceptable safety. This evidence addresses an important gap in knowledge of treatment outcomes in adolescents with HCV/HIV coinfection in real-life settings.