학술논문
DEFB1 gene 5′ untranslated region (UTR) polymorphisms are marginally involved in inflammatory bowel disease in south Brazilians
Document Type
Academic Journal
Author
Source
International Journal of Immunogenetics. Apr 01, 2014 41(2):138-142
Subject
Language
English
ISSN
1744-3121
Abstract
The possible association of three DEFB1 gene polymorphisms with susceptibility to develop ulcerative colitis (UC) and Crohnʼs disease (CD) was investigated in Brazilian patients and controls. Although a clear and strong association between functional 5′-UTR DEFB1 SNPs and susceptibility/protection to IBDs cannot be drawn, our results suggest a possible involvement of DEFB1 gene in inflammatory bowel diseases, especially with the colonic localization of Crohnʼs disease.