학술논문

Effects of naloxone on the breathing pattern of a newborn exposed to maternal opiates
Document Type
Academic Journal
Source
Acta Paediatrica. Jul 01, 2012 101(7):e309-e312
Subject
Language
English
ISSN
0803-5253
Abstract
AIM:: To give new insights into how an infant responded to naloxone, given after acquiring a maternal opiate by recording the breathing pattern directly after birth. METHOD:: A respiratory recording is presented of an infant during resuscitation in the delivery room after receiving naloxone for respiratory depression, resulting from maternal remifentanyl use. RESULTS:: The infant was born apneic and bradycardic. Normal resuscitation manoeuvres had no effect on the respiratory drive. Directly after administration of naloxone, a tachypneic breathing pattern with sporadic expiratory breaking manoeuvres was observed. CONCLUSION:: The immediate tachypnoea is most likely a direct effect of the naloxone causing an immediate ‘rebound response’ after the release of the opiate-induced inhibition of the respiratory drive.