학술논문
68Ga-LNC-1007 PET/CT Imaging in a Patient With Renal Cell Carcinoma Compared With 68Ga-PSMA-11 PET/CT
Document Type
Academic Journal
Author
Source
Clinical Nuclear Medicine. Dec 01, 2023 48(12):1119-1121
Subject
Language
English
ISSN
0363-9762
Abstract
ABSTRACT: A 57-year-old man was incidentally found with 3 lesions located in bilateral kidneys, which were finally diagnosed as renal cell carcinoma (RCC) by postoperative pathology. Ga-LNC-1007, also denoted as Ga-FAPI-RGD, was synthesized from fibroblast activation protein inhibitor-02 (FAPI-02) and cyclic arginine-glycine-aspartate (RGD), which could target both FAP and integrin αvβ3. RCC lesions demonstrated only slight Ga-PSMA uptake, but intense tracer uptake on Ga-LNC-1007 PET/CT. This case demonstrates the potential value of Ga-LNC-1007 PET/CT for the evaluation of RCC.