학술논문
Haemodynamic crisis and reversible multiorgan failure caused by HIV post-exposure prophylaxis after needle-stick injury in a health care worker
Document Type
Academic Journal
Author
Source
HIV Medicine. Mar 01, 2004 5(2):125-127
Subject
Language
English
ISSN
1464-2662
Abstract
We report the case of a 59-year-old nurse from our HIV ward who developed a severe haemodynamic crisis with concomitant acute multiorgan failure after initiation of a post-exposure prophylaxis (PEP) with zidovudine/lamivudine (Combivir™) and lopinavir/ritonavir (Kaletra™) after a needle-stick injury with an HIV-contaminated needle. Although serious and life-threatening adverse effects of post-exposure prophylaxis have been documented in several cases, this is the first report of a severe acute cardiovascular incident following PEP initiation.